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Dennis Meredith is writing a science thriller, the Tasty Bomb [] in which an eccentric main character, having been reprimanded for her foul mouth, has decided to employ non-curse words in her vocabulary as substitutes. The "Curse word" Challenge: come up with words whose sound makes them satisfying curses in times of anger or frustration. Examples:
Fricassee!
Pork chop!
Chopstick!

Mother Puss Bucket

Strubnubbit!
Crashit!
Shitake!
Bug monkey (derogatory for sci fi implying a dronelike worker)
Connectionless or linkless (implying friendless)

Another option, if set in a earth based future would be to fall back to Shakespeare. Always some great insults there. "Away, you starvelling, you elf-skin, you dried neat's tongue, bull's pizzle, you stock-fish!" or "Away, you three-inch fool!"

Here are a couple
Horse hockey!
Bullfeathers!

I will add a real-world example of just such an instance - when my wife (who swears worse than I do) was admonished to tone it down in front of the children (who were in elementary school at the time), she started using "Glitter" as a substitute for curse words.

Believe me, after telling someone to "Glitter-off" or "Glitter you" a few times, you'll be wishing the curse words were back.

My late business partner, and best friend, could curse for an hour straight without repeating himself or using a "bad" word.

One of his favorites (instead of something like "sh*t") was "Ten thousand blue pigs!"

One of my characters used "God's breath!"

Wankel Rotary Engine