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“It would be very hard for you to live a happy life if you were covered in wiggling, buzzing tiny crabs that you could never get rid of.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“your immune system is also not a singular thing. It is a complex and interconnected collection of hundreds of bases and recruitment centers all over your body.”
― Philipp Dettmer, Immune: A journey into the system that keeps you alive - the book from KURZGESAGT IN A NUTSHELL

“An antigen is a piece of an enemy that your immune system can recognize.”
― Philipp Dettmer, Immune: A journey into the system that keeps you alive - the book from KURZGESAGT IN A NUTSHELL

“there is a vicious part of measles that is not discussed as much as the disease itself: Kids who overcome a measles infection have a higher chance of getting other diseases afterwards because the measles virus kills Memory Cells. If you think that sounds a bit scary, that is the correct reaction—the virus basically deletes your acquired immunity.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“The best way to kill a lot of viruses is to destroy infected cells, and the viruses inside them. Let us pause for a moment to appreciate the magnitude of what we are talking about here. Your immune system needs to be able to kill your own cells. Your immune system has an actual license to kill you.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“hot dog bun on the Dendritic Cell can only hold wieners. In contrast, the B Cell receptors are not as picky.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“The immune system is the most complex biological system known to humanity, other than the human brain.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“At its very core, the immune system is a tool to distinguish the other from the self. It does not matter if the other means to harm you or not. If the other is not on a very exclusive guest list that grants free passage, it has to be attacked and destroyed because the other might harm you. In the world of the immune system, any “otherâ€� is not a risk worth taking. Without this commitment you would die within days. And as we will learn later, sadly, when your immune system under- or overcommits, death or suffering are the consequences.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“But all that was just to buy time. It takes about two to three days until Natural Killer Cells show up and begin to alleviate your desperately fighting immune soldiers. They flood the tissue and begin killing infected epithelial cells, especially the ones that were manipulated by the influenza A virus to hide their display windows, their MHC class I molecules, but not exclusively them. The more stressed and desperate infected cells get mercifully finished off, to end their suffering but also to prevent them from causing further harm.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“1% of the DNA is made up of sequences that are building manuals for proteins, which are called Genes. The rest of your DNA is regulating which proteins are built when and how and how many of them at which time.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“How do your cells know in which order to put amino acids to make the proteins they need? Well, this is the job of the code of life: Your DNA, a long sequence of instructions that are necessary for a living thing to be a living thing.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“Proteins are made from chains of amino acids, which are tiny organic building blocks that come in twenty different varieties. All you need to do is to string them together into a chain, in whatever order you like, and voila, you have a protein.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“cells protein robots.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“cells have “organsâ€� that are called organelles, like the nucleus, the information center of your cell—a pretty large structure with its own protective border wall that houses your DNA, your genetic code. There are mitochondria, generators that transform food and oxygen into chemical energy that keeps your cells running. There is a specialized transport network, a packaging center, parts for digestion and recycling, construction centers.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“cells are biological robots, driven entirely by myriads of biochemical reactions guided by the even smaller parts they are made up from.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“cells are the smallest units of life:”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“distinguishing between self and other is core, homeostasis is the goal, and there are seemingly infinite ways for it to all go wrong.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“Something that can’t be overemphasized enough about the immune system is how much it tries to be balanced and how much care it puts into calming itself down and not overreacting.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“identifying what is self and what is other is the core, it is not technically the goal of your immune system. The goal above all things is maintaining and establishing homeostasis: the equilibrium between all the elements and cells in the body.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“What is generally troubling about these appeals to naturalism is the idea itself, that something natural is somehow better. Nature does not care about you or any individual at all. Your brain and body and immune system are built on the bones of billions of your would-be ancestors who were not fast enough to escape a lion, were killed by a mild infection, or were just a little worse at pulling the nutrients from their food. Nature gave us charming diseases like smallpox, cancer, rabies, and parasitic worms that feast on the eyes of your children. Nature is cruel and without any form of care for you. Our ancestors fought tooth and nail to build a different world for themselves, a world without all this suffering and pain and horror. And consequently we should celebrate and marvel at the enormous progress we’ve made as a species. While we obviously still have a long way to go and the modern world has a lot of downsides, the notion that “natural is betterâ€� is something only people who are not actually living in nature can say, and who have forgotten why our ancestors worked so hard to escape it.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“deaths from COVID-19 come from the immune system doing its job with too much enthusiasm.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“Life hates nothing as much as wasting resources.”
― Philipp Dettmer, Immune: a Journey into the Mysterious System that Keeps You Alive

“effective tools to prevent screaming (cytokine release) by doing a bit of stabbing.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“The Neutrophil is a bit of a simpler fellow. It exists to fight and to die for the collective. It is the crazy suicidal Spartan warrior of the immune system. Or if you want to stay in the animal kingdom, a chimp on coke with a bad temper and a machine gun.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“mRNA”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“Early in an infection this has the upside that while the adaptive immune system is still booting up and is not in full combat mode, IgM Antibodies are already making the innate immune system more deadly and more precise.”
― Philipp Dettmer, Immune: A journey into the system that keeps you alive - the book from KURZGESAGT IN A NUTSHELL

“Jemanden gut riechen können,”
― Philipp Dettmer, Immune: A journey into the system that keeps you alive - the book from KURZGESAGT IN A NUTSHELL

“If you have measles, you’re so contagious that 90% of all susceptible people that come close to you will be infected just by being in your vicinity. So if you have it and other, non-vaccinated people share a subway train or a classroom with you, it is highly likely that you will infect others.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive

“cute butts for friends.”
― Philipp Dettmer, Immune: A Journey Into the Mysterious System That Keeps You Alive