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Although I gave this book a five-star rating, I have somewhat mixed feelings about it. First, the writing is excellent, at least in the chapters I understood. The problem for me was that the first two parts of the book were pretty technical. I have a degree in physics but you almost need a degree in chemistry and biology to follow some of the narrative. I'm getting older and I tend to like books that are easy to read. But, the final two chapters made the book worth the price. In the next to last chapter he lists eleven things we can do to live longer. Most of these we know (exercise, eat right, get enough sleep, etc.) But for me the real reward was in the final chapter where he writes about metformin, a drug that is used to treat diabetes. Research has shown that the drug may also reduce the risk of cancer and dementia and extend lifespan by a bit. I'm going to call my doctor tomorrow to see if she'll prescribe it!